Komissarov I V, Larina T F, Ginzburg O A, Sheĭnkman A K
Farmakol Toksikol. 1976 May-Jun;39(3):286-9.
1-(N-piperidine-acetyl)-2,3-dihydroindoles display high activity in infiltration and conduction anestheia, exceeding that of trimecaine. N-alkylaminoacetyl-indolines are moderately active, while N-morpholine and N-indolylacetyl-indolines are practically inactive when employed in the given types of local anesthesia. All the N-substituted aminoacetyl-indolines are little active in terminal anesthesia.
1-(N-哌啶基-乙酰基)-2,3-二氢吲哚在浸润麻醉和传导麻醉中表现出高活性,超过三甲卡因。N-烷基氨基乙酰基吲哚啉活性中等,而N-吗啉基和N-吲哚基乙酰基吲哚啉在给定类型的局部麻醉中实际无活性。所有N-取代氨基乙酰基吲哚啉在表面麻醉中活性都很低。