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利用碱性吉姆萨染色对体细胞杂种中的种间染色体进行差异染色。

Differential staining of interspecific chromosomes in somatic cell hybrids by alkaline Giemsa stain.

作者信息

Friend K K, Chen S, Ruddle F H

出版信息

Somatic Cell Genet. 1976 Mar;2(2):183-8. doi: 10.1007/BF01542631.

DOI:10.1007/BF01542631
PMID:1028166
Abstract

Staining of chromosome preparations of Chinese hamster-human hybrid cells and mouse-chimpanzee hybrids with alkaline Giemsa has yielded color differentiation of the interspecific chromosomes. Bicolor chromosomes, indicating apparent translocations also are observed for each of these hybrids. The specific color differences observed provide a rapid means of recognizing and aiding in the identification of the interspecific chromosomes and apparent translocations in these somatic cell hybrids.

摘要

用碱性吉姆萨对中国仓鼠-人类杂交细胞和小鼠-黑猩猩杂交细胞的染色体标本进行染色,已实现种间染色体的颜色分化。在这些杂交细胞中,还观察到了双色染色体,这表明存在明显的易位现象。所观察到的特定颜色差异为识别和辅助鉴定这些体细胞杂种中的种间染色体及明显易位提供了一种快速方法。

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Differential staining of interspecific chromosomes in somatic cell hybrids by alkaline Giemsa stain.利用碱性吉姆萨染色对体细胞杂种中的种间染色体进行差异染色。
Somatic Cell Genet. 1976 Mar;2(2):183-8. doi: 10.1007/BF01542631.
2
Detection of interspecific translocations in mouse-human hybrids by alkaline Giemsa staining.
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[Simultaneous activity of nucleolus organizer regions of human and Chinese hamster chromosomes in somatic cell hybrids].[人及中国仓鼠染色体核仁组织区在体细胞杂种中的同步活性]
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Exp Cell Res. 1983 Oct;148(1):265-72. doi: 10.1016/0014-4827(83)90207-0.

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5
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Studies of the locus for androgen receptor: localization on the human X chromosome and evidence for homology with the Tfm locus in the mouse.雄激素受体基因座的研究:定位于人类X染色体以及与小鼠Tfm基因座同源性的证据。
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