Seeman T E, Guralnik J M, Kaplan G A, Knudson L, Cohen R
J Aging Health. 1989 Feb;1(1):50-66. doi: 10.1177/089826438900100104.
Longitudinal data from the Alameda County Study are used to examine three health consequences of multiple or co-morbidity, defined as the coexistence of two or more chronic conditions and/or symptoms. Age-adjusted analyses of the consequences of baseline co-morbidity show significant associations in both age groups with 17-year mortality, and with the development of multiple new conditions and the occurrence of depression over a 9-year follow-up. After adjustments for sociodemographic characteristics and health behaviors, all associations with multiple new conditions remain significant. The association with depressive symptoms, however, remains significant for the younger age group only and the association with mortality become nonsignificant in both age groups.
阿拉米达县研究的纵向数据用于检验多重或共病的三种健康后果,多重或共病定义为两种或更多慢性疾病和/或症状的共存。对基线共病后果的年龄调整分析显示,在两个年龄组中,共病与17年死亡率、多种新疾病的发生以及9年随访期间抑郁症的发生均存在显著关联。在对社会人口学特征和健康行为进行调整后,与多种新疾病的所有关联仍然显著。然而,与抑郁症状的关联仅在较年轻年龄组中仍然显著,而与死亡率的关联在两个年龄组中均变得不显著。