Paskhina T S
Biokhimiia. 1976 Aug;41(8):1347-51.
The literature data on some new functions of human plasma kallikrein have been discussed. The role of kallikrein as an enzymatic activator of Hageman factor in fluid-phase was emphasized, and the description of this effect, brought about by a feedback mechanism was given. These new findings stress the importance of plasma kallikrein in the initiation of kinin-forming, intrinsing clotting and fibrinolysis. The chemotactic activity of the kallikrein molecule for human neurophiles was considered. New data were given concerning Hageman factor as proteinase and its substrates in human plasma-coagulation factor XI (PTA), plasminogen proectivator and prekallikrein.
已讨论了关于人血浆激肽释放酶一些新功能的文献资料。强调了激肽释放酶在液相中作为Hageman因子的酶激活剂的作用，并给出了由反馈机制产生的这种效应的描述。这些新发现强调了血浆激肽释放酶在激肽形成、内源性凝血和纤维蛋白溶解起始过程中的重要性。考虑了激肽释放酶分子对人嗜中性粒细胞的趋化活性。给出了关于Hageman因子作为蛋白酶及其在人血浆凝血因子XI（PTA）、纤溶酶原激活物和前激肽释放酶中的底物的新数据。
