Sohn C A, Wolter H A, McSweeney G W
Drug Intell Clin Pharm. 1980 Apr;14(4):272-7. doi: 10.1177/106002808001400406.
In October, 1977, a cephalosporin drug-use review and an educational program were initiated to maximize savings in the pharmacy budget at UCSF and to revise the formulatory to include only one parenteral cephalosporin. The results of the drug-use review were presented to the Pharmacy and Therapeutics Committee where our proposal for an education campaign to encourage appropriate dosing of cefazolin was approved. An explanatory document comparing cephalosporin costs and equivalency was developed for hospital-wide distribution. Pharmacy staffs were informed of program objectives to coordinate education efforts. Physician education was undertaken via document and personal contact with pharmacy personnel. A drug-use review one month after institution of the cephalosporin education program showed marked changes in physician prescribing habits, with greater impact on services where pharmacists were members of the medical rounding team. A change to appropriate dosage prescribing of cefazolin resulted in significant cost savings to the pharmacy budget. These findings resulted in formulary revision to cefazolin as the single cephalosporin available at UCSF. Because cefazolin is available from more than one manufacturer, we were able to obtain a lower bid price the following year, thus realizing an additional cost savings.
1977年10月,启动了一项头孢菌素药物使用审查和教育计划,以最大限度地节省加州大学旧金山分校药房预算,并修订配方集,使其仅包含一种肠胃外头孢菌素。药物使用审查的结果提交给了药学与治疗学委员会,在那里我们关于开展教育活动以鼓励合理使用头孢唑林剂量的提议获得了批准。一份比较头孢菌素成本和等效性的解释性文件被制定出来,供全院分发。药房工作人员被告知项目目标,以协调教育工作。通过文件以及与药房人员的个人接触对医生进行教育。头孢菌素教育计划实施一个月后的药物使用审查显示,医生的处方习惯有了显著变化,对药剂师作为医疗查房团队成员的服务产生了更大影响。将头孢唑林的处方剂量改为合适剂量后,药房预算大幅节省。这些结果导致将配方集修订为以头孢唑林作为加州大学旧金山分校唯一可用的头孢菌素。由于头孢唑林有多个制造商生产,我们能够在次年获得更低的投标价格,从而实现了额外的成本节约。