Komáromi I
Acta Physiol Acad Sci Hung. 1976;47(1):15-27.
5-Hydroxytryptamine (10 microgram), gamma-amino-butyric acid (20 microgram) and carbachol (1 microgram) were injected through the soft skull into the lateral cerebral ventricle of guinea pigs aged 2 to 12 days, at the slightly subneutral ambient temperature of 30 degrees C. 5-Hydroxytryptamine (5-HT) produced no immediate change in oxygen consumption, whereas colonic temperature fell rapidly. One hour after injecting 5-HT, when colonic temperature had decreased by about 0.5 degrees C, oxygen consumption increased and after a lag of 30--40 min was followed by an increase in colonic temperature. Gamma-amino-butyric acid (GABA) increased oxygen consumption and colonic temperature after a latency of 30--60 min. Carbachol was followed by an immediate decrease in colonic temperature and oxygen consumption. Colonic temperature was below the pre-injection level throughout the five-hour period of observation.
在30摄氏度略低于中性的环境温度下，将5-羟色胺（10微克）、γ-氨基丁酸（20微克）和卡巴胆碱（1微克）通过豚鼠柔软的颅骨注入2至12日龄豚鼠的侧脑室。5-羟色胺（5-HT）注射后耗氧量无立即变化，而结肠温度迅速下降。注射5-HT一小时后，当结肠温度下降约0.5摄氏度时，耗氧量增加，在滞后30 - 40分钟后结肠温度升高。γ-氨基丁酸（GABA）在30 - 60分钟的潜伏期后增加耗氧量和结肠温度。卡巴胆碱注射后结肠温度和耗氧量立即下降。在整个五小时的观察期内，结肠温度低于注射前水平。
