Johnsen N J, Dam M, Thomsen J, Zilstorff K
Clin Otolaryngol Allied Sci. 1976;1(3):225-32. doi: 10.1111/j.1365-2273.1976.tb00881.x.
A clinical vestibular examination was carried out on 82 patients with multiple sclerosis (MS) selected on McAlpine's criteria. Spontaneous nystagmus, positional nystagmus or pathological caloric test were found in 49 (60%) patients. Pathological horizontal optokinetic nystagmus occurred in 47 (57%) patients. In 36 cases horizontal optokinetic nystagmus was pathological to both sides, in 28 cases combined with a pathological vertical optokinetic nystagmus, indicative of diffuse intracerebral lesions. Lesions in the central vestibular system and in the optokinetic pathways were frequently discovered in early or atypical cases of MS.
根据麦卡尔平标准选取了82例多发性硬化症（MS）患者进行临床前庭检查。49例（60%）患者出现自发性眼球震颤、位置性眼球震颤或病理性冷热试验。47例（57%）患者出现病理性水平视动性眼球震颤。36例患者双侧水平视动性眼球震颤均为病理性，28例合并病理性垂直视动性眼球震颤，提示弥漫性脑内病变。在前庭系统和视动通路的病变在MS的早期或非典型病例中经常被发现。
