Analysis of the acidic fraction of marijuana smoke condensate by capillary gas chromatography-mass spectrometry.

A method for the analysis of organic acids and phenols isolated from marijuana smoke condensate has been developed. Comparative analyses of standard tobacoo, Mexican, and Turkish marijuana smoke condensates carried out by means of capillary gas chromatography indicated both qualitative and quantitative changes in the constituents of chromatographic profiles. Samples were converted to volatile derivatives by methylation and trimethylsilylation; whereupon, 49 aliphatic acids, aromatic acids, and phenolic compounds were identified by means of capillary gas chromatography-mass spectrometry.