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大麻烟雾冷凝物样本的制备与监测

Preparation and monitoring of marijuana smoke condensate samples.

作者信息

Patel A R, Gori G B

出版信息

Bull Narc. 1975 Jul-Sep;27(3):47-54.

PMID:241444
Abstract

The objective of this study was the production of smoke condensate from the marijuana cigarettes on schedule for the bioassay study and involved quality control on each batch of smoke condensate. Examination of the condensate production data (tables 1 and 2) reveal that it is not possible to strictly control the butt length of cigarettes when smoked on a robot smoking machine thereby accounting for some variation in the yield of the dry particulate matter and increment9-tetrahydrocannabinol. No increment8-tetrahydrocannabinol was detected in any batch of the smoke condensate. Recently, Hoffman and co-workers (13) have reported that marijuana that exhibited carcinogenic potential similar to tobacco cigarette smoke condensate in the dermal assay in mice.

摘要

本研究的目的是按计划为生物测定研究生产大麻卷烟的烟雾冷凝物,并对每批烟雾冷凝物进行质量控制。对冷凝物生产数据(表1和表2)的检查表明,在机器人吸烟机上吸烟时,无法严格控制卷烟的滤嘴长度,从而导致干颗粒物和增量9-四氢大麻酚的产量存在一些差异。在任何一批烟雾冷凝物中均未检测到增量8-四氢大麻酚。最近,霍夫曼及其同事(13)报告称,在小鼠皮肤试验中,大麻表现出与烟草卷烟烟雾冷凝物相似的致癌潜力。

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