Salamon A, Hámori J
Acta Morphol Acad Sci Hung. 1976;24(1-2):11-22.
Collagen synthesis has been studied in preserved autologous and homologous tendon grafts, applied in dogs. The stages of collagen morphogenesis observed in the synthetizing fibroblasts appearing in the decomposing original structure of the transplants as well as in the extracellular ground substance are described. The results suggest that autologous tendon grafts and homologous ones preserved by irradiation, stored in cold physiological saline and beta-propiolactone, are rebuilt within eight weeks; meanwhile the original collagenous fibre structure is decomposed. When other preserving procedures such as deep-freezing or gamma irradiation are applied recomposition of the graft is retarded or fails to occur; the result is a cicatrizing adhesion.
已对应用于犬的保存自体和同种异体肌腱移植物中的胶原蛋白合成进行了研究。描述了在移植体分解的原始结构以及细胞外基质中出现的合成成纤维细胞中观察到的胶原形态发生阶段。结果表明，通过辐照保存、储存在冷生理盐水和β-丙内酯中的自体肌腱移植物和同种异体肌腱移植物在八周内重建；同时，原始胶原纤维结构分解。当应用其他保存程序，如深度冷冻或γ辐照时，移植物的重组会延迟或无法发生；结果是形成瘢痕粘连。
