Mondragón Sánchez R J, Castillero Pinilla C, Saldívar Moreno C, Oñate Ocaña L F, Ruiz Molina J M, Aiello Crocifoglio V
Departamento de Gastroenterología, Instituto Nacional de Cancerología, México D.F.
Rev Gastroenterol Mex. 1998 Oct-Dec;63(4):204-10.
Carcinoid tumors are rare, most of the publications are case reports and the clinical series are uncommon. The quality of life and survival time of these patients depend on the adequate control of tumor growth and good palliation of their symptoms.
The purpose of this study is to inform epidemiological data and forms of management for these tumors and the Carcinoid Syndrome at the National Institute of Cancerology (INCan) at Mexico City in the last 15 years.
A retrospective review of the clinical records of patients diagnosed and treated at the INCan with carcinoid tumors from 1982 to 1997 was performed.
The most common origin place was the gastrointestinal tract (GI), and the majority involved the right colon and the appendix. The longest survivors were patients with tumors originated in the appendix, tumors smaller than 2 cm or localized. At the time of diagnosis 47% of patients had metastatic disease that was also a poor prognostic factor. The experience in our hospital seem to support the use of interferon alone or in combination with octreotide or debulking surgery for the palliation of carcinoid syndrome.
Carcinoid tumors are rare, and have a slow growth and less aggressive biological nature than noncarcinoid tumors. Treatment should be focused on trying to cure the small or localized lesions or to find the best palliative method for those symptomatic advanced lesions.
类癌肿瘤较为罕见，大多数出版物为病例报告，临床系列报道并不常见。这些患者的生活质量和生存时间取决于肿瘤生长的充分控制以及症状的良好缓解。
本研究旨在提供过去15年在墨西哥城国家癌症研究所（INCan）这些肿瘤及类癌综合征的流行病学数据和管理方式。
对1982年至1997年在INCan诊断和治疗的类癌肿瘤患者的临床记录进行回顾性分析。
最常见的起源部位是胃肠道（GI），大多数累及右结肠和阑尾。存活时间最长的是肿瘤起源于阑尾、肿瘤小于2厘米或局限的患者。诊断时47%的患者有转移性疾病，这也是一个不良预后因素。我们医院的经验似乎支持单独使用干扰素或与奥曲肽联合使用或减瘤手术来缓解类癌综合征。
类癌肿瘤罕见，生长缓慢，生物学特性比非类癌肿瘤侵袭性小。治疗应侧重于尝试治愈小的或局限性病变，或为那些有症状的晚期病变找到最佳的姑息治疗方法。
