Tóth Miklós, Prónai László, Németh Anna Mária, Tulassay Zsolt
Orv Hetil. 2002 May 12;143(19 Suppl):1087-92.
Carcinoids are characteristically indolent, but heterogeneous tumors with respect to their site of origin, endocrine features, clinical manifestations and biologic behaviour. The authors summarize the current laboratory, endoscopic and radiologic methods used for the diagnosis of carcinoid tumors. Treatment modalities should be directed against the tumor and the hormonal excess state. The authors review the outcome of most frequently used therapies, including somatostatin-analogue and interferon treatment, chemotherapy, embolization, receptor-targeted radiotherapy and surgical intervention). Patients with carcinoid tumors, with or without carcinoid syndrome, are best managed by a multidisciplinary approach.
类癌通常生长缓慢,但在起源部位、内分泌特征、临床表现和生物学行为方面具有异质性。作者总结了目前用于诊断类癌肿瘤的实验室、内镜和放射学方法。治疗方式应针对肿瘤和激素分泌过多状态。作者回顾了最常用治疗方法的疗效,包括生长抑素类似物和干扰素治疗、化疗、栓塞、靶向受体放疗和手术干预。类癌肿瘤患者,无论有无类癌综合征,最好采用多学科方法进行管理。