Stamatakos M, Kontzoglou K, Sargedi C, Tsaknaki S, Iannescu R, Safioleas C, Kaitanidi V, Safioleas M
4th Department of Surgery, University of Athens, School of Medicine, Attikon General Hospital, Athens, Greece.
Chirurgia (Bucur). 2010 Nov-Dec;105(6):759-66.
Carcinoid tumors are malignancies originating from neuroendocrine cells, most commonly encountered in the gastrointestinal tract, in a rate of 64%, with the majority affecting the ileum. Certain genetic syndromes sometimes include carcinoid tumors in their phenotype. These malignancies may be rather asymptomatic, although occasionally they behave aggressively. They are typically diagnosed due to the effects of a locally advanced disease, or when producing symptoms because of hormone secretion (carcinoid syndrome). A better understanding of their molecular biology and behavior is demanded so that these tumors to be diagnosed precociously and managed effectively.
类癌肿瘤是起源于神经内分泌细胞的恶性肿瘤，最常见于胃肠道，发生率为64%，其中大多数影响回肠。某些遗传综合征有时在其表型中包括类癌肿瘤。这些恶性肿瘤可能相当无症状，尽管偶尔它们会表现出侵袭性。它们通常是由于局部晚期疾病的影响而被诊断出来的，或者是在因激素分泌而产生症状（类癌综合征）时被诊断出来的。需要更好地了解它们的分子生物学和行为，以便能早熟诊断并有效治疗这些肿瘤。
