大鼠脊髓移植胶质瘤的扩散张量磁共振成像与组织学对比研究
Diffusion tensor MR imaging and comparative histology of glioma engrafted in the rat spinal cord.
作者信息
Inglis B A, Neubauer D, Yang L, Plant D, Mareci T H, Muir D
机构信息
Department of Neuroscience, University of Florida, Gainesville 32610, USA.
出版信息
AJNR Am J Neuroradiol. 1999 Apr;20(4):713-6.
Abstract
MR imaging using contrast material derived from the diffusion of tissue water was tested for its ability to provide a nondestructive histologic analysis of tumor morphology. An apparent diffusion tensor MR image of a glioma engrafted within a rat spinal cord was generated in which fiber orientation in three dimensions was displayed in color. This imaging method clearly separated tumor from host white and gray matter and corresponded well with conventional histologic microscopy.
摘要
利用源自组织水扩散的造影剂进行的磁共振成像（MR成像），被测试其提供肿瘤形态学无损组织学分析的能力。生成了大鼠脊髓内移植的神经胶质瘤的表观扩散张量MR图像，其中三维纤维取向以彩色显示。这种成像方法能清晰地将肿瘤与宿主白质和灰质区分开来，且与传统组织学显微镜检查结果吻合良好。
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