Kain Z N, Wang S M, Mayes L C, Caramico L A, Hofstadter M B
Department of Anesthesiology, Yale School of Medicine, New Haven, Connecticut, USA.
Anesth Analg. 1999 May;88(5):1042-7. doi: 10.1097/00000539-199905000-00013.
We determined whether children who are extremely anxious during the induction of anesthesia are more at risk of developing postoperative negative behavioral changes compared with children who appear calm during the induction process. Children (n = 91) aged 1-7 yr scheduled for general anesthesia and elective outpatient surgery were recruited. Using validated measures of preoperative anxiety and postoperative behaviors, children were evaluated during the induction of general anesthesia and on Postoperative Days 1, 2, 3, 7, and 14. Using a multivariate logistic regression model, in which the dependent variable was the presence or absence of postoperative negative behavioral changes and the independent variables included several potential predictors, we demonstrated that anxiety of the child, time after surgery, and type of surgical procedure were predictors for postoperative maladaptive behavior. The frequency of negative postoperative behavioral changes decreased with time after surgery, and the frequency of negative postoperative behavioral changes increased when the child exhibited increased anxiety during the induction of anesthesia. Finally, we found a significant correlation (r) of 0.42 (P = 0.004) between the anxiety of the child during induction and the excitement score on arrival to the postanesthesia care unit. We conclude that children who are anxious during the induction of anesthesia have an increased likelihood of developing postoperative negative behavioral changes. We recommend that anesthesiologists advise parents of children who are anxious during the induction of anesthesia of the increased likelihood that their children will develop postoperative negative behavioral changes such as nightmares, separation anxiety, and aggression toward authority.
Anesthesiologists who care for children who are anxious during the induction of anesthesia should inform parents that these children have an increased likelihood of developing postoperative negative behavioral changes.
我们确定了与麻醉诱导过程中表现平静的儿童相比,麻醉诱导期间极度焦虑的儿童术后出现负面行为变化的风险是否更高。招募了计划接受全身麻醉和择期门诊手术的1至7岁儿童(n = 91)。使用经过验证的术前焦虑和术后行为测量方法,在全身麻醉诱导期间以及术后第1、2、3、7和14天对儿童进行评估。使用多变量逻辑回归模型,其中因变量是术后负面行为变化的有无,自变量包括几个潜在预测因素,我们证明儿童的焦虑、术后时间和手术类型是术后适应不良行为的预测因素。术后负面行为变化的频率随术后时间的推移而降低,当儿童在麻醉诱导期间焦虑增加时,术后负面行为变化的频率会增加。最后,我们发现诱导期间儿童的焦虑与到达麻醉后护理单元时的兴奋评分之间存在显著相关性(r)为0.42(P = 0.004)。我们得出结论,麻醉诱导期间焦虑的儿童术后出现负面行为变化的可能性增加。我们建议麻醉医生告知在麻醉诱导期间焦虑的儿童的家长,他们的孩子术后出现负面行为变化(如噩梦、分离焦虑和对权威的攻击性)的可能性增加。
照顾在麻醉诱导期间焦虑的儿童的麻醉医生应告知家长,这些儿童术后出现负面行为变化的可能性增加。