El-Hawary M F, Sakr R, Khalek M K, Abdin M, Maraghi S
Gaz Egypt Paediatr Assoc. 1976 Jul-Oct;24(3-4):119-32.
Fifty-nine bilharzial subjects aged 9-12 years and 18 parallel controls were investigated for total serum proteins, total liver proteins and total urinary proteins. Simple agar gel and immunoelectrophoretic studies were also carried out. The results revealed a highly significant decrease in serum total proteins in mixed infection. A very highly significant increase was demonstrated for serum alpha, globulin. The gamma globulin fraction and the total globulin moiety were very highly significantly raised. The albumin globulin ratio was considerably decreased in mansoniasis. Serum immunoelectrophoresis illustrated a decreased density of haptoglobulin, hemopexin and transferrin arcs, as well as a considerable increase in IgA, IgM and IgG in most of the cases. Urinary protein values were very highly significantly elevated in hematobiasis and mixed infection. A slight increase for alpha1, alpha2 and beta-globulins was found in some cases. Liver proteins were very highly significantly decreased in mansoniasis and mixed infection. The results are discussed and analysed.
对59名9至12岁的血吸虫病患者和18名平行对照者进行了血清总蛋白、肝脏总蛋白和尿总蛋白的检测。还进行了简单琼脂凝胶和免疫电泳研究。结果显示，混合感染时血清总蛋白显著降低。血清α1球蛋白有非常显著的升高。γ球蛋白部分和总球蛋白部分非常显著升高。曼氏血吸虫病患者的白蛋白球蛋白比值显著降低。血清免疫电泳显示，大多数病例中触珠蛋白、血红素结合蛋白和转铁蛋白弧的密度降低，同时IgA、IgM和IgG显著增加。尿路血吸虫病和混合感染时尿蛋白值非常显著升高。在某些病例中发现α1、α2和β球蛋白略有增加。曼氏血吸虫病和混合感染时肝脏蛋白非常显著降低。对结果进行了讨论和分析。
