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[切除颈上神经节后不同时期脑细胞核和线粒体核糖核酸酶活性的变化]

[Changes in the ribonuclease activity of brain cell nuclei and mitochondria at different periods following removal of the superior cervical sympathetic ganglion].

作者信息

Mkheian E E, Karapetian T D

出版信息

Vopr Biokhim Mozga. 1976;11:143-50.

PMID:1032217
Abstract

A study of the changes in the ribonuclease activity of nuclei and mitochondria of rat brain cells following 1, 3, 7, 20 and 90 days after extirpation of the right superior cervical ganglion showed an increase of enzyme activity in nuclei from the first up to the 90-th day following removal of the ganglion. During the first three days after the operation enzyme activity is higher in nuclei obtained from the intact (left) side of the brain while later on enzyme activity is more pronounced in nuclei obtained from the right (sympathectomized) side of the brain. In mitochondria enzyme activity is depressed during the whole period studied after sympathectomy (90 days).

摘要

一项关于大鼠右上颈神经节切除术后1天、3天、7天、20天和90天,其脑细胞的细胞核和线粒体中核糖核酸酶活性变化的研究表明,在切除神经节后第1天至第90天,细胞核中的酶活性增加。术后头三天,取自大脑完整(左侧)的细胞核中的酶活性较高,而之后取自大脑右侧(交感神经切除)的细胞核中的酶活性更为明显。在交感神经切除术后的整个研究期间(90天),线粒体中的酶活性受到抑制。

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