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[切除颈上交感神经节后大鼠脑细胞核酸核部分的定量变化]

[Quantitative changes in the nucleic acid nuclear fraction of rat brain cells following removal of the superior cervical sympathetic ganglion].

作者信息

Mkheian E E, Karapetian T D

出版信息

Vopr Biokhim Mozga. 1974;9:181-8.

PMID:4471550
Abstract

The nucleic acid content of the nuclear fraction of cerebral hemispheres was studied 1, 3, 7, 20 and 90 days after unilateral removal of superior cervical ganglion. The results obtained indicate that the content of nuclear RNA is significantly reduced in the desympathized side 1 day after removal of the ganglion. Seven days after sympathectomy the content of RNA increases, reaching control levels. Beginning from the 20th day it decreases and remains at a low level for 90 days. This decrease is observed on both sides of the brain. The content of nuclear DNA is significantly reduced seven days following removal of superior cervical ganglion. The possible mechanisms of the alterations observed are discussed in connection with changes in correlation of nucleic acids with nuclear proteins.

摘要

在单侧切除颈上神经节后1天、3天、7天、20天和90天,研究了大脑半球核部分的核酸含量。所得结果表明,切除神经节后1天,去交感神经一侧的核RNA含量显著降低。交感神经切除术后7天,RNA含量增加,达到对照水平。从第20天开始下降,并在90天内维持在低水平。大脑两侧均观察到这种下降。切除颈上神经节后7天,核DNA含量显著降低。结合核酸与核蛋白相关性的变化,讨论了观察到的改变的可能机制。

相似文献

1
[Quantitative changes in the nucleic acid nuclear fraction of rat brain cells following removal of the superior cervical sympathetic ganglion].[切除颈上交感神经节后大鼠脑细胞核酸核部分的定量变化]
Vopr Biokhim Mozga. 1974;9:181-8.
2
[Role of the superior cervical sympathetic ganglion on regulating the amount of brain cell nuclear histones].颈上神经节在调节脑细胞核对组蛋白含量中的作用
Vopr Biokhim Mozga. 1978;13:138-43.
3
[Changes in the ribonuclease activity of brain cell nuclei and mitochondria at different periods following removal of the superior cervical sympathetic ganglion].[切除颈上神经节后不同时期脑细胞核和线粒体核糖核酸酶活性的变化]
Vopr Biokhim Mozga. 1976;11:143-50.
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[Change in the ATP content and ATPase activity in albino rat brain following extirpation of the right superior cervical sympathetic ganglion].[右侧颈上神经节切除后白化大鼠脑内ATP含量及ATP酶活性的变化]
Vopr Biokhim Mozga. 1972;7(0):172-5.
5
[The influence of prolonged painful stimulation on adrenaline and noradrenaline concentration in different regions of the brain and in the adrenals of white rats before and after removal of the superior cervical sympathetic ganglia].[长时间疼痛刺激对切除颈上交感神经节前后大白鼠大脑不同区域及肾上腺中肾上腺素和去甲肾上腺素浓度的影响]
Fiziol Zh SSSR Im I M Sechenova. 1975 Mar;61(3):385-90.
6
[Effect of fixation in Carnoy's solution on nucleic acid and protein concentration in the rabbit superior cervical sympathetic ganglion].[卡诺氏液固定对兔颈上神经节核酸和蛋白质浓度的影响]
Tsitologiia. 1977;19(1):90-4.
7
[Effect of histological processing on the nucleic acid, free nucleotide and protein content in the cranial cervical sympathetic ganglion].[组织学处理对颅颈交感神经节中核酸、游离核苷酸和蛋白质含量的影响]
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[Changes in nucleic acid and protein content in different regions of the brain is rats reared in enriched and impoverished environments].[在丰富和贫瘠环境中饲养的大鼠大脑不同区域核酸和蛋白质含量的变化]
Zh Vyssh Nerv Deiat Im I P Pavlova. 1982 May-Jun;32(3):455-62.
9
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Tsitologiia. 1967 Nov;9(11):1378-84.
10
[Basophilic changes in the anterior pituitary after the extirpation of superior cervical sympathetic ganglia in the rat].[大鼠颈上交感神经节切除后垂体前叶的嗜碱性变化]
Izv Akad Nauk SSSR Biol. 1965 Jan-Feb;1:113-8.