Mkheian E E, Kocharian K M
Vopr Biokhim Mozga. 1978;13:138-43.
The quantitative changes of histones and their fractions and of nonhistone proteins in nuclei of cerebral cells have been studied in normal animals and following removal of the right superior cervical ganglion. On the next day after sympathectomy the total amount of histones was shown to increase by 17% in nuclei of cells of the right hemisphere while in nuclei of cells of the left hemisphere an increase of 38% was observed 3 days after sympathectomy. Histone fractions rich in lysine were also found to increase. The amount of nonhistone proteins begins to decrease on the next day after sympathectomy and reaches 33% of control values by the third day.
已经对正常动物以及切除右侧颈上神经节后大脑细胞核中组蛋白及其组分和非组蛋白的定量变化进行了研究。交感神经切除术后第二天，右侧半球细胞核中的组蛋白总量增加了17%，而交感神经切除术后3天，左侧半球细胞核中的组蛋白总量增加了38%。富含赖氨酸的组蛋白组分也有所增加。非组蛋白的量在交感神经切除术后第二天开始减少，到第三天降至对照值的33%。
