Wodarz D, Nowak M A, Bangham C R
Institute for Advanced Study, Olden Lane, Princeton, NJ 08540, USA.
Immunol Today. 1999 May;20(5):220-7. doi: 10.1016/s0167-5699(99)01446-2.
Dominik Wodarz and colleagues describe a mathematical model for the in vivo dynamics of human T-cell leukaemia virus type 1 (HTLV-I) infection and the virus-specific cytotoxic T lymphocyte response. They show that a high rate of viral replication is consistent with the relative sequence invariance of HTLV-I and might be necessary to maintain a persistent infection.
多米尼克·沃达兹及其同事描述了一种关于1型人类T细胞白血病病毒（HTLV-I）感染的体内动力学以及病毒特异性细胞毒性T淋巴细胞反应的数学模型。他们表明，高病毒复制率与HTLV-I的相对序列不变性相一致，并且可能是维持持续性感染所必需的。
