γ-羟基丁酸：一种具有滥用潜力的内源性神经调节剂？ - Suppr

Gamma-hydroxybutyric acid: an endogenous neuromodulator with abuse potential?

作者信息

Bernasconi R, Mathivet P, Bischoff S, Marescaux C

机构信息

INSERM Unit 398, Neurobiologie et Neuropharmacologie des Epilepsies Généralisées, Hôpitaux Universitaires, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France.

出版信息

Trends Pharmacol Sci. 1999 Apr;20(4):135-41. doi: 10.1016/s0165-6147(99)01341-3.

DOI:10.1016/s0165-6147(99)01341-3

PMID:10322498

Abstract

摘要

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Gamma-hydroxybutyric acid: an endogenous neuromodulator with abuse potential?

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相似文献

Gamma-hydroxybutyric acid: an endogenous neuromodulator with abuse potential?

Trends Pharmacol Sci. 1999 Apr;20(4):135-41. doi: 10.1016/s0165-6147(99)01341-3.

Gamma-hydroxybutyric acid as a signaling molecule in brain.

Alcohol. 2000 Apr;20(3):277-83. doi: 10.1016/s0741-8329(99)00092-0.

Abuse and therapeutic potential of gamma-hydroxybutyric acid.

Alcohol. 2000 Apr;20(3):263-9. doi: 10.1016/s0741-8329(99)00090-7.

Gamma-hydroxybutyric acid.

N Engl J Med. 2005 Jun 30;352(26):2721-32. doi: 10.1056/NEJMra044047.

Unravelling the brain targets of gamma-hydroxybutyric acid.

Curr Opin Pharmacol. 2006 Feb;6(1):44-52. doi: 10.1016/j.coph.2005.10.001. Epub 2005 Dec 20.

Gamma-hydroxybutyric acid: a medicine or a drug of abuse?

South Med J. 2002 Aug;95(8):793-4. doi: 10.1097/00007611-200208000-00002.

Experience with sodium-gamma-4-hydroxybutyric acid (gamma-OH) in obstetrics.

J Obstet Gynaecol Br Commonw. 1968 Apr;75(4):405-13. doi: 10.1111/j.1471-0528.1968.tb00137.x.

gamma-Hydroxybutyric acid is not a GABA-mimetic agent in the spinal cord.

Ann Neurol. 1979 Aug;6(2):111-6. doi: 10.1002/ana.410060206.

Safety and tolerability of gamma-hydroxybutyric acid in the treatment of alcohol-dependent patients.

Alcohol. 2000 Apr;20(3):223-5. doi: 10.1016/s0741-8329(99)00085-3.

Commenting on"a review of tolerability and abuse liability of gamma-hydroxybutyric acid for insomnia in patients with schizophrenia," by Kantrowitzet al.

Clin Ther. 2010 Apr;32(4):780-5. doi: 10.1016/j.clinthera.2010.04.006.

引用本文的文献

Metabolic Alterations in Premutation Carriers.

Front Mol Biosci. 2020 Sep 18;7:571092. doi: 10.3389/fmolb.2020.571092. eCollection 2020.

Diversity of structure and function of GABA receptors: a complexity of GABA-mediated signaling.

Proc Jpn Acad Ser B Phys Biol Sci. 2018;94(10):390-411. doi: 10.2183/pjab.94.026.

Allopregnanolone Treatment Improves Plasma Metabolomic Profile Associated with GABA Metabolism in Fragile X-Associated Tremor/Ataxia Syndrome: a Pilot Study.

Mol Neurobiol. 2019 May;56(5):3702-3713. doi: 10.1007/s12035-018-1330-3. Epub 2018 Sep 5.

GHB acid: A rage or reprive.

J Adv Pharm Technol Res. 2013 Oct;4(4):173-8. doi: 10.4103/2231-4040.121410.

New synthesis and tritium labeling of a selective ligand for studying high-affinity γ-hydroxybutyrate (GHB) binding sites.

J Med Chem. 2013 Oct 24;56(20):8201-5. doi: 10.1021/jm4011719. Epub 2013 Oct 4.

α4βδ GABA(A) receptors are high-affinity targets for γ-hydroxybutyric acid (GHB).

Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13404-9. doi: 10.1073/pnas.1204376109. Epub 2012 Jul 2.

Succinic semialdehyde dehydrogenase: biochemical-molecular-clinical disease mechanisms, redox regulation, and functional significance.

Antioxid Redox Signal. 2011 Aug 1;15(3):691-718. doi: 10.1089/ars.2010.3470. Epub 2011 Apr 10.

Liquid ecstasy - a significant drug problem.

Dtsch Arztebl Int. 2008 Sep;105(36):599-603. doi: 10.3238/arztebl.2008.0599. Epub 2008 Sep 5.

Antagonism of phencyclidine-induced stimulus control in the rat by other psychoactive drugs.

Pharmacol Biochem Behav. 2008 Jan;88(3):189-95. doi: 10.1016/j.pbb.2007.07.007. Epub 2007 Aug 15.

Attributing effects of aqueous C60 nano-aggregates to tetrahydrofuran decomposition products in larval zebrafish by assessment of gene expression.

Environ Health Perspect. 2007 Jul;115(7):1059-65. doi: 10.1289/ehp.9757.

Gamma-hydroxybutyric acid: an endogenous neuromodulator with abuse potential?

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