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苏格兰野兔副结核病的流行病学研究。

Epidemiological study of paratuberculosis in wild rabbits in Scotland.

作者信息

Greig A, Stevenson K, Henderson D, Perez V, Hughes V, Pavlik I, Hines M E, McKendrick I, Sharp J M

机构信息

SAC Veterinary Science Division, Perth PH1 1HF, Scotland, United Kingdom.

出版信息

J Clin Microbiol. 1999 Jun;37(6):1746-51. doi: 10.1128/JCM.37.6.1746-1751.1999.

Abstract

A survey of 22 farms confirmed the presence of paratuberculosis in wild rabbits in Scotland. Regional differences were apparent in the prevalence of the disease in rabbits, with a significantly higher incidence occurring in the Tayside region. Statistical analysis showed a significant relationship between a previous history or current problem of paratuberculosis in cattle and the presence of paratuberculosis in rabbits on the farms. Molecular genetic typing techniques could not discriminate between selected rabbit and cattle isolates from the same or different farms, suggesting that the same strain may infect and cause disease in both species and that interspecies transmission may occur. The possibility of interspecies transmission and the involvement of wildlife in the epidemiology of paratuberculosis have important implications for the control of the disease.

摘要

一项对22个农场的调查证实,苏格兰的野兔中存在副结核病。该病在野兔中的流行存在地区差异,泰赛德地区的发病率明显更高。统计分析表明,牛群既往或当前存在副结核病问题与农场中野兔感染副结核病之间存在显著关联。分子遗传分型技术无法区分来自同一或不同农场的选定兔和牛的分离株,这表明同一菌株可能感染这两个物种并导致疾病,且可能发生种间传播。种间传播的可能性以及野生动物参与副结核病的流行病学对该病的防控具有重要意义。

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