Peyrade F, Taillan B, Lebrun C, Dujardin P
Service d'Hématologie-Médecine interne, Hôpital de Cimiez, Nice.
Presse Med. 1999 Apr 17;28(15):809-14.
As the HIV epidemic advances, the spectrum of non-AIDS defining malignancy is expanding. Recent reports suggest an increased incidence of skin cancers, squamous cell carcinomas of the anus, and Hodgkin's disease in HIV-infected patients. Other neoplasms encountered in this setting include oral mucosa, head and neck carcinoma without evidence of increased incidence. PARTICULAR FEATURES: The natural history of lung, testicle and skin cancer (excepting Kaposi sarcoma) as well as ENT cancer appears to be modified in HIV-infected patients. The main problem raised by these tumors is confounding infection which may lead to late diagnosis or an error in tumor staging.
随着艾滋病毒疫情的发展,非艾滋病定义性恶性肿瘤的范围正在扩大。最近的报告显示,艾滋病毒感染患者的皮肤癌、肛门鳞状细胞癌和霍奇金病的发病率有所增加。在这种情况下遇到的其他肿瘤包括口腔黏膜、头颈部癌,但发病率没有增加的证据。特殊特征:艾滋病毒感染患者的肺癌、睾丸癌和皮肤癌(卡波西肉瘤除外)以及耳鼻喉癌的自然史似乎有所改变。这些肿瘤引发的主要问题是合并感染,这可能导致诊断延迟或肿瘤分期错误。