Bunn B K, van Heerden W F P
Department of Oral Pathology and Oral Biology, School of Dentistry, Faculty of Health Sciences, University of Pretoria.
SADJ. 2012 Nov;67(10):590-2.
Patients with HIV/AIDS are at increased risk for the development of malignancy. Kaposi's sarcoma, non-Hodgkin's lymphoma and cervical carcinoma in women are regarded as AIDS-defining malignancies. The spectrum of malignancy is, however, changing, particularly where patients receive highly active antiretroviral therapy (HAART). South Africa has the highest number of HIV-infected individuals globally. The possibility of the oral health care worker encountering HIV/AIDS-related pathology therefore seems inevitable. The aim of this article is to heighten the awareness of head and neck malignancies occurring in HIV/AIDS whilst highlighting some of the clinical features in order to facilitate early recognition and diagnosis. It is of clinical significance that in many instances, identification of these malignancies precedes HIV/AIDS diagnosis. Optimal patient management requires close co-operation between the oral health care practitioner and the extended health care team.
感染人类免疫缺陷病毒/获得性免疫综合征(HIV/AIDS)的患者发生恶性肿瘤的风险增加。卡波西肉瘤、非霍奇金淋巴瘤和女性宫颈癌被视为艾滋病界定的恶性肿瘤。然而,恶性肿瘤的范围正在发生变化,尤其是在患者接受高效抗逆转录病毒治疗(HAART)的情况下。南非是全球HIV感染者人数最多的国家。因此,口腔医护人员遇到与HIV/AIDS相关病理情况的可能性似乎不可避免。本文旨在提高对HIV/AIDS患者发生的头颈部恶性肿瘤的认识,同时突出一些临床特征,以便于早期识别和诊断。在许多情况下,这些恶性肿瘤的识别先于HIV/AIDS诊断,这具有临床意义。最佳的患者管理需要口腔医护人员与扩大的医疗团队密切合作。