Br J Gen Pract. 1999 Feb;49(439):95-8.
Major depression is an illness with a high prevalence and is most commonly seen and treated by general practitioners (GPs).
To determine the level of disability in depressed patients seen in a primary care setting, and to investigate whether the level of disability was associated with the severity of the depression.
Prospective data collection, using the 36-item Shortened Form (SF-36), from the Medical Outcomes Study, as a measure of disability, and from the Beck Depression Inventory (BDI) in a sample of depressed patients recruited from a Counselling versus Antidepressant in Primary Care (CAPC) study in the Trent Region. All patients met the research diagnostic criteria for major depression.
Two hundred and fifty patients were assessed. These patients reported high levels of disability compared both with published norms and with other chronic physical illnesses. Increases in disability were especially noticeable in the domains of the SF-36 that were specific to mental illness. There was a significant correlation between scores on the SF-36 and the BDI.
This study confirms that depressed patients in primary care report high levels of disability on the SF-36, and that the instrument is both specific to the domains expected to be affected by mental disorder and is sensitive to the severity of mood disturbance.
重度抑郁症是一种高患病率的疾病,全科医生(GPs)最常诊治此类疾病。
确定在初级保健机构中就诊的抑郁症患者的残疾程度,并调查残疾程度是否与抑郁症的严重程度相关。
采用前瞻性数据收集方法,使用医学结局研究中的36项简短形式(SF - 36)作为残疾程度的衡量指标,并使用贝克抑郁量表(BDI)对从特伦特地区初级保健中的咨询与抗抑郁药(CAPC)研究招募的抑郁症患者样本进行评估。所有患者均符合重度抑郁症的研究诊断标准。
对250名患者进行了评估。与已发表的标准以及其他慢性身体疾病相比,这些患者报告的残疾程度较高。在SF - 36中特定于精神疾病的领域,残疾程度的增加尤为明显。SF - 36得分与BDI得分之间存在显著相关性。
本研究证实,初级保健中的抑郁症患者在SF - 36上报告的残疾程度较高,并且该工具既特定于预期受精神障碍影响的领域,又对情绪障碍的严重程度敏感。