Cuddigan J, Frantz R A
Adv Wound Care. 1998 Oct;11(6):294-300; quiz 302.
The AHCPR guideline on Treatment of Pressure Ulcers was released in December 1994. This guideline was based on the best available scientific evidence published between 1966 and May 1, 1993. Over 45,000 abstracts were reviewed in the literature analysis. Yet only 63.2% of the guideline recommendations were based on research of any type, and only 4.5% of the recommendations were supported by two or more randomized clinical trials. A more recent literature review (covering articles on pressure ulcers listed in the MEDLINE database between May 1, 1993, and December 1, 1996), revealed minimal advances in the scientific body of knowledge on pressure ulcer treatment. Advances have been made in the knowledge of electrical therapy and growth factors, and efforts are under way to enhance tools for monitoring healing. In an era of limited research funding, we need to carefully target our research efforts to maximize the advancement of our knowledge of pressure ulcer treatment. It is the hope of the NPUAP that this monograph will guide the research needed to ensure the most efficient utilization of funds to improve patient outcomes.
美国卫生保健政策与研究署（AHCPR）的压疮治疗指南于1994年12月发布。该指南基于1966年至1993年5月1日期间发表的最佳科学证据。在文献分析中审查了超过45,000篇摘要。然而，该指南的建议中只有63.2%基于任何类型的研究，只有4.5%的建议得到两项或更多随机临床试验的支持。最近的一项文献综述（涵盖1993年5月1日至1996年12月1日期间MEDLINE数据库中列出的关于压疮的文章）显示，压疮治疗科学知识方面进展甚微。在电疗法和生长因子知识方面取得了进展，并且正在努力改进愈合监测工具。在研究资金有限的时代，我们需要谨慎地确定研究方向，以最大限度地推动我们对压疮治疗知识的进步。国家压力性溃疡咨询小组（NPUAP）希望这本专著将指导所需的研究，以确保最有效地利用资金来改善患者预后。
