Czeizel A
Acta Paediatr Acad Sci Hung. 1976;17(2):123-34.
Surveillance of congenital anomalies has various functions viz. monitoring (to detect clusters as soon as possible), registering (to contribute to medical care and to provide material for scientific research) and informative. The Hungarian Congenital Malformation Register records the occurrence of malformed babies diagnosed from birth to 1 year of age. The Register has 3 sources (obstetricians, paediatricians, pathologists) and has registered since 1971 over 4000 malformed infants annually, an occurrence of over 28%. Validity and completeness of notification depend on the type of malformation. A separate Monitor started on January 1st, 1973, is confined to congenital malformations detectable unequivocally and readily during the first seven days of life. So far four real clusters occurred in Hungary but their causes could not be found. Particular stress has been laid upon multiple malformations (syndromes) since all known teratogens affecting humans produce multiple malformations.
先天性异常监测具有多种功能,即监测(尽快发现聚集性病例)、登记(为医疗保健提供支持并为科研提供素材)以及提供信息。匈牙利先天性畸形登记处记录从出生到1岁被诊断出的畸形婴儿的情况。该登记处有3个信息来源(产科医生、儿科医生、病理学家),自1971年以来每年登记超过4000名畸形婴儿,发生率超过28%。报告的有效性和完整性取决于畸形的类型。一个单独的监测项目于1973年1月1日启动,仅限于在出生后前七天能够明确且容易检测到的先天性畸形。到目前为止,匈牙利出现了4个真正的聚集性病例,但尚未找到其原因。由于所有已知影响人类的致畸物都会导致多种畸形,所以特别关注了多发畸形(综合征)。