Desai K, Robson H G
Department of Medicine, Royal Victoria Hospital, Montreal, Quebec, Canada.
Sex Transm Dis. 1982 Jan-Mar;9(1):21-5. doi: 10.1097/00007435-198201000-00004.
The diagnostic sensitivity of the numbers of leukocytes in the sediment of first-voided urine and in gram-stained smears of urethral secretions was evaluated by a study of 62 men with symptoms of nongonococcal urethritis. Fifty-one patients (82.3%) had pyuria (defined as ten or more leukocytes per high-power field) in the sediment of first-voided urine, whereas 8 (45.2%) had more than four leukocytes per oil-immersion held in gram-stained urethral smears. Frequencies of positive first-voided urine sediments and urethral smears were similar in Chlamydia trachomatis--positive and -negative cases. Results of cultures, urinalyses, and urethral smears were not affected by recent micturition. Pyuria in the first-voided urine but not a positive urethral smear is a sensitive sign of urethritis whether or not urethral discharge is evident. Specimens of urethral secretions were subjected to different storage conditions to determine the effect on subsequent isolation of C. trachomatis. Equal rates of isolation were demonstrated for specimens that had been held at 4 degrees C for either four or 20-24 hr or frozen to -70 degrees C for one week prior to culture.
通过对62名有非淋菌性尿道炎症状的男性进行研究，评估了首次晨尿沉渣中白细胞数量以及尿道分泌物革兰氏染色涂片的诊断敏感性。51名患者（82.3%）首次晨尿沉渣中有脓尿（定义为每高倍视野有10个或更多白细胞），而8名患者（45.2%）革兰氏染色尿道涂片中每油镜视野有超过4个白细胞。沙眼衣原体阳性和阴性病例中，首次晨尿沉渣和尿道涂片阳性的频率相似。培养、尿液分析和尿道涂片的结果不受近期排尿的影响。无论尿道分泌物是否明显，首次晨尿中的脓尿而非尿道涂片阳性是尿道炎的敏感体征。对尿道分泌物标本进行不同的储存条件处理，以确定对随后沙眼衣原体分离的影响。在培养前，于4℃保存4小时或20 - 24小时，或冷冻至 - 70℃保存一周的标本，其分离率相同。
