Ijaiya K, Schwenk A, Gladtke E
Dtsch Med Wochenschr. 1976 Oct 22;101(43):1563-8. doi: 10.1055/s-0028-1104303.
The fetal alcohol syndrome was observed in four girls aged 1 2/12 to 9 2/12 years, two of whom were sisters. Three of the children are older than all others previously described as having this syndrome. The signs consist of a decrease of body length and weight beginning at birth, microcephalus, marked decrease of intelligence and narrowing of the palpebral fissure. Frequently congenital cardiac defects are found and sometimes anomalies of the genitalia and other malformations. Experience so far indicates a causal relationship between considerable alcohol abuse of mothers during pregnancy and intra-uterine fetal damage. The prognosis is poor; in severe cases of chronic alcoholism interruption of pregnancy should be seriously considered.
在4名年龄为1岁2个月至9岁2个月的女孩中观察到胎儿酒精综合征，其中两名是姐妹。这4名儿童中有3名比之前描述的所有患有该综合征的儿童年龄都大。体征包括自出生起身长和体重下降、小头畸形、智力显著下降以及睑裂狭窄。常发现先天性心脏缺陷，有时还有生殖器异常和其他畸形。目前的经验表明，母亲在孕期大量酗酒与子宫内胎儿损伤之间存在因果关系。预后很差；在严重慢性酒精中毒的情况下，应认真考虑终止妊娠。
