高原相关肺部疾病

Altitude-related pulmonary disorders.

作者信息

Krieger B P, de la Hoz R E

机构信息

Division of Pulmonary and Critical Care, University of Miami at Mount Sinai Medical Center, Florida, USA.

出版信息

Crit Care Clin. 1999 Apr;15(2):265-80, viii. doi: 10.1016/s0749-0704(05)70054-3.

DOI:10.1016/s0749-0704(05)70054-3

PMID:10331128

Abstract

The major physiologic stress encountered at high altitude is caused by the occurrence of hypobaric hypoxia. In this article, acute and chronic pulmonocardiac adaptation to altitude is reviewed, including possible genetic differences among highlanders from the Himalayan versus the Andean Mountains. The origin, symptoms, and treatment of acute mountain sickness and high altitude pulmonary edema are outlined. In addition, the prediction and prevention of pulmonary complications that may be encountered or exacerbated during commercial airflight are noticed.

摘要

在高海拔地区遇到的主要生理应激是由低气压性缺氧引起的。本文综述了对海拔高度的急性和慢性心肺适应性，包括来自喜马拉雅山脉与安第斯山脉的高原居民之间可能存在的基因差异。概述了急性高原病和高原肺水肿的起源、症状及治疗方法。此外，还提到了在商业飞行过程中可能遇到或加重的肺部并发症的预测和预防。