急性高原病和高原肺水肿的病理生理学：一种假说。

Pathophysiology of acute mountain sickness and high altitude pulmonary oedema: an hypothesis.

作者信息

Sutton J R, Lassen N

出版信息

Bull Eur Physiopathol Respir. 1979 Sep-Oct;15(5):1045-52.

Abstract

We review the evidence that acute mountain sickness (AMS) and high altitude pulmonary oedema (HAPO) occur together more often than is realized. We hypothesize that AMS and HAPO have a common pathophysiological basis: both are due to increased pressure and flow in the microcirculation, causing oedema in the brain and oedema in the lungs.

摘要

我们回顾了相关证据，即急性高原病（AMS）和高原肺水肿（HAPO）同时发生的频率比人们意识到的更高。我们推测，AMS和HAPO有共同的病理生理基础：两者均归因于微循环中压力和血流增加，从而导致脑水肿和肺水肿。