Orbital chondrosarcoma developing in a patient with Paget disease.
作者信息
Mooy C M, Naus N C, de Klein A, van den Bosch W A, Paridaens D A
机构信息
Department of Pathology, Erasmus University Rotterdam, The Netherlands.
出版信息
Am J Ophthalmol. 1999 May;127(5):619-21. doi: 10.1016/s0002-9394(98)00405-x.
PURPOSE
To describe the radiologic, histopathologic, and cytogenetic features of an orbital chondrosarcoma developing in a patient with Paget disease.
METHODS
A 64-year-old woman presented with rapidly progressive proptosis of her right eye. Computed tomographic scans, histopathologic examination, and cytogenetic analysis were performed.
RESULTS
Computed tomographic scans disclosed osseous changes of the temporal and frontal bones, with areas of high density consistent with Paget disease. A soft-tissue tumor in the right lateral orbital wall was consistent with Paget sarcoma. On histology, a chondrosarcoma was diagnosed, which was confirmed by fluorescent in situ hybridization.
CONCLUSION
This is a unique case of orbital chondrosarcoma developing in a patient with Paget disease.
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