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[小脑实验性胚细胞瘤形成过程中的卵巢形态学]

[Ovarian morphology during experimental blastomogenesis in the cerebellum].

作者信息

Faustov L A

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(12):1784-7.

PMID:103347
Abstract

A morphological and histochemical study of the ovaries in 79 rats with cerebellar blastomogenesis due to DMBA in comparison with the ovaries of intact rats, rats with trauma of the cerebellum, rats with a paraffin pill implanted into the cerebellum, as well as with the ovaries of rats with a chemical cancerogenesis of the intestine, permitted to claim, that the most characteristic changes of the ovaries in cerebellar blastomogenesis consist in reduced amount of premordial follicules, athresia of the growing follicles and a formation of multiple follicular cysts. These processes are underlain by destruction of premordial follicles and a degeneration of the ovule in the growing follicles.

摘要

对79只因二甲基苯蒽(DMBA)导致小脑母细胞瘤形成的大鼠的卵巢进行形态学和组织化学研究,并与完整大鼠、小脑创伤大鼠、小脑植入石蜡丸的大鼠以及肠道化学致癌大鼠的卵巢进行比较,结果表明,小脑母细胞瘤形成时卵巢最典型的变化包括原始卵泡数量减少、生长卵泡闭锁以及多个卵泡囊肿形成。这些过程的基础是原始卵泡的破坏和生长卵泡中胚珠的退化。

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