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[大白鼠小脑化学致癌过程中非典型神经胶质间充质成分中的DNA含量]

[DNA content in atypical gliomesenchymal elements in chemical blastomogenesis of the cerebellum in white rats].

作者信息

Kazantseva I A, Iablonovskaia L Ia

出版信息

Biull Eksp Biol Med. 1975 Oct;80(10):96-9.

PMID:819059
Abstract

A microphotometric comparative study was carried out; DNA content was determined in the atypical glio-mesenchymal elements around the villous capsule surrounding the DMBA pill, in the cells of microastrocytoma and microglioblastoma induced by DMBA. It was found that the late stages of this type of chemical blastomogenesis of the cerebellum of albino rats were characterized by the preservation of a distinct diploid modal class, excluding cases when the process coursed in the direction of malignization at the early stages of tumour progress (microglioblastoma).

摘要

进行了一项显微光度比较研究;测定了二甲基苯并蒽(DMBA)药丸周围绒毛膜囊周围非典型神经胶质-间充质成分以及DMBA诱导的微星形细胞瘤和微胶质母细胞瘤细胞中的DNA含量。结果发现,白化大鼠小脑这种化学性胚细胞瘤形成的晚期阶段的特征是保留明显的二倍体模态类别,但肿瘤进展早期过程朝着恶性化方向发展的情况(微胶质母细胞瘤)除外。

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