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杜氏肌营养不良症中的红细胞形态。

Erythrocyte shape in Duchenne muscular dystrophy.

作者信息

Matheson D W, Engel W K, Derrer E C

出版信息

Neurology. 1976 Dec;26(12):1182-3. doi: 10.1212/wnl.26.12.1182.

Abstract

In a controlled and blind study we were not able to identify any abnormality of erythrocytes of eight patients with Duchenne muscular dystrophy compared with seven approximately age-matched unaffected siblings (six males, one female step-sibling). Erythrocyte morphology was found to be very sensitive to various types of cell treatment. At this time, erythrocyte morphology, evaluated by the techniques used, should not be considered an established diagnostic test for the Duchenne muscular dystrophy patient or carrier.

摘要

在一项对照盲法研究中,与7名年龄大致匹配的未患病同胞(6名男性,1名女性继兄弟姐妹)相比,我们未能识别出8例杜氏肌营养不良症患者红细胞的任何异常。发现红细胞形态对各种类型的细胞处理非常敏感。此时,通过所使用的技术评估的红细胞形态,不应被视为杜氏肌营养不良症患者或携带者的既定诊断测试。

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