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高效抗逆转录病毒治疗时代的艾滋病治疗

HIV disease treatment in the era of HAART.

作者信息

Bonfanti P, Capetti A, Rizzardini G

机构信息

1st Department of Infectious Diseases and Allergy, Luigi Sacco Hospital, Milan, Italy.

出版信息

Biomed Pharmacother. 1999 Mar;53(2):93-105. doi: 10.1016/s0753-3322(99)80066-3.

Abstract

In the last three years basic science and clinical research have radically changed the therapeutical approach to HIV disease. Recent guidelines suggest that treatments to HIV disease should be early and aggressive, with the use of new potent antiretroviral drugs. This approach has been defined as HAART (highly active antiretroviral therapy). In this review we will discuss the main stages of antiretroviral therapy focusing on the acquisitions about results as well as problems of triple therapy.

摘要

在过去三年里,基础科学和临床研究彻底改变了对艾滋病的治疗方法。最近的指南建议,对艾滋病的治疗应尽早且积极进行,使用新型强效抗逆转录病毒药物。这种方法被定义为高效抗逆转录病毒治疗(HAART)。在这篇综述中,我们将讨论抗逆转录病毒治疗的主要阶段,重点关注三联疗法的疗效及问题方面所取得的进展。

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