Maucour M F, Brugniart C, Ducasse A, Brasme L, Bajolet O
Service d'Ophtalmologie, CHUR de Reims.
J Fr Ophtalmol. 1999 Apr;22(3):371-6.
Bacillary endophthalmitis occurring after penetrating ocular trauma with an intraocular foreign body is always associated with poor visual outcome. Bacilli cause fulminant infection associated with tissue damage in the intraocular structures.
Our series consisted of four patients with penetrating ocular trauma and endophthalmitis caused by B. cereus or B. licheniformis. Three eyes ultimately developed phtisis. Only on eye recovered good vision (2.5/10 P4).
Recommended early treatment includes topical, subconjunctival, parenteral antibiotics. A review of the literature indicates that intravitreal antibiotic infusion is crucial for sufficient concentration to control infection. Early vitrectomy is recommended in the management of endophthalmitis. Vitreous and intraocular foreign bodies should be cultured to identify pathogens and ascertain antibiotic susceptibilities.
眼内异物穿透性眼外伤后发生的细菌性眼内炎通常与视力预后不良相关。芽孢杆菌会引发暴发性感染，并伴有眼内结构的组织损伤。
我们的系列研究包括4例由蜡样芽孢杆菌或地衣芽孢杆菌引起的穿透性眼外伤和眼内炎患者。最终，3只眼发展为眼球痨。只有1只眼恢复了良好视力（2.5/10 P4）。
推荐的早期治疗包括局部、结膜下、肠道外使用抗生素。文献综述表明，玻璃体内注入抗生素对于达到控制感染的足够浓度至关重要。在眼内炎的治疗中推荐早期进行玻璃体切除术。应对玻璃体和眼内异物进行培养，以识别病原体并确定抗生素敏感性。
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