一名9岁男孩患鲁宾斯坦-泰比综合征和眉部干性糠疹

Rubinstein--Taybi syndrome and ulerythema ophryogenes in a 9-year-old boy.

作者信息

Gómez Centeno P, Rosón E, Peteiro C, Mercedes Pereiro M, Toribio J

机构信息

Department of Dermatology, General Hospital of Galicia, Faculty of Medicine, Santiago de Compostela, Spain.

出版信息

Pediatr Dermatol. 1999 Mar-Apr;16(2):134-6. doi: 10.1046/j.1525-1470.1999.00032.x.

DOI:10.1046/j.1525-1470.1999.00032.x

PMID:10337678

Abstract

Rubinstein-Taybi syndrome is characterized by the presence of a peculiar facies, mental retardation, and broad thumbs and great toes. Several associated cutaneous abnormalities have been reported with this syndrome. Ulerythema ophryogenes is a form of follicular keratosis associated occasionally with other ectodermal defects and congenital anomalies. We describe a 9-year-old child with Rubinstein-Taybi syndrome and ulerythema ophryogenes. This association has not been described previously to our knowledge.

摘要

鲁宾斯坦-泰比综合征的特征是具有特殊面容、智力迟钝以及宽阔的拇指和大脚趾。已有报道称该综合征伴有多种相关的皮肤异常。眉部瘢痕性红斑是毛囊角化病的一种形式，偶尔与其他外胚层缺陷及先天性异常相关。我们描述了一名患有鲁宾斯坦-泰比综合征和眉部瘢痕性红斑的9岁儿童。据我们所知，此前尚未有过这种关联的报道。