Mani J, Chaudhary N, Ravat S, Shah P U
Department of Neurology, KEM Hospital, Parel, Mumbai, 400012, India.
Neurol India. 1999 Mar;47(1):8-11.
31 patients of multiple sclerosis (MS) diagnosed in the last six years in a large teaching hospital were reviewed. The hospital incidence of 0.85% of total admissions in neurology unit in western India is comparable to the series from other parts of India. The mean age at onset was slightly lower compared to other series. The female preponderence was noted in addition to higher incidence of Devic's syndrome. Visual loss (47%) and motor weakness (27%) were the commonest presenting symptoms. The clinical pattern was more similar to Asian series of MS than the western series. All patients underwent magnetic resonance imaging (MRI) scan. 24 out of 25 MRI of Brain and 15 out of 16 MRI of spine were abnormal. CSF immuno-globulins were raised in 80% of patients who underwent CSF study. The data has been compared with other Indian, Asian and Western series.
对一家大型教学医院在过去六年中诊断出的31例多发性硬化症(MS)患者进行了回顾。印度西部该医院神经科病房的发病率占总入院人数的0.85%,与印度其他地区的系列数据相当。发病的平均年龄比其他系列略低。除了视神经脊髓炎谱系疾病(Devic's syndrome)发病率较高外,还发现女性占优势。视力丧失(47%)和运动无力(27%)是最常见的首发症状。临床模式与亚洲多发性硬化症系列比与西方系列更为相似。所有患者均接受了磁共振成像(MRI)扫描。25例脑部MRI中有24例异常,16例脊柱MRI中有15例异常。接受脑脊液研究的患者中80%脑脊液免疫球蛋白升高。已将该数据与其他印度、亚洲和西方系列数据进行了比较。