Rossant J
J Embryol Exp Morphol. 1976 Oct;36(2):283-90.
Blastomeres isolated from 4- and 8-cell mouse eggs were inserted into empty zonae and transferred to the oviduct. The products of both types of blastomere were capable of inducing decidual formation. One implant produced by an isolated blastomere from a 4-cell egg contained a small, retarded embryo at 5 1/2 days but most decidua from blastomeres of either 4- or 8-cell eggs contained only a few trophoblast giant cells. It is suggested that this lack of totipotency is due to insufficient cells being present at cavitation rather than restriction in developmental potential.
从4细胞和8细胞小鼠卵中分离出的卵裂球被植入空透明带并转移至输卵管。两种类型卵裂球的产物都能够诱导蜕膜形成。一个由4细胞卵的分离卵裂球产生的植入物在5.5天时含有一个小的、发育迟缓的胚胎，但来自4细胞或8细胞卵的卵裂球形成的大多数蜕膜仅含有少数滋养层巨细胞。有人提出，这种全能性的缺乏是由于在空泡化时细胞数量不足，而不是发育潜能受到限制。
