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避孕药的介绍及其影响。

Introduction of the pill and its impact.

作者信息

Tyrer L

出版信息

Contraception. 1999 Jan;59(1 Suppl):11S-16S. doi: 10.1016/s0010-7824(98)00131-0.

Abstract

Introduction of the birth control pill in the United States in 1960 marked the end of a relatively short period of time (< 10 years) to intentionally produce an oral contraceptive, and the beginning of a relatively long period of controversy surrounding the use of the pill. Availability of the pill had an impact on various aspects of social life, including women's health, fertility trends, laws and policies, religion, interpersonal relationships and family roles, feminist issues, and gender relations, as well as sexual practices among both adults and adolescents. The pill proved to be highly effective from the outset. Although safety issues developed with the earlier formulations, continued evolution of pill hormones and doses has resulted in a greatly improved and safe oral contraceptive. A broad range of noncontraceptive health benefits also is associated with the pill. These health effects are significant, as they include protection against potentially fatal diseases, including ovarian and endometrial cancers, as well as against other conditions that are associated with substantial morbidity and potential hospitalization and associated costs. The popularity of the pill has remained high, with rates of use in the past 30 years in the United States ranging from one-quarter to almost one-third of women using contraception. Almost 40 years after its introduction, the pill's contraceptive efficacy is proven, its improved safety has been established, and the focus has shifted from supposed health risks to documented and real health benefits.

摘要

1960年避孕药在美国的问世标志着一段相对较短时期(不到10年)有意生产口服避孕药的结束,以及围绕避孕药使用的一段较长争议时期的开始。避孕药的可获得性对社会生活的各个方面都产生了影响,包括女性健康、生育趋势、法律与政策、宗教、人际关系与家庭角色、女权主义问题以及性别关系,还有成年人和青少年的性行为。避孕药从一开始就被证明非常有效。尽管早期配方存在安全问题,但避孕药激素和剂量的不断演变已带来了极大改进且安全的口服避孕药。避孕药还具有广泛的非避孕健康益处。这些健康影响意义重大,因为它们包括预防潜在致命疾病,如卵巢癌和子宫内膜癌,以及预防其他会导致大量发病、可能住院及相关费用的疾病。避孕药的受欢迎程度一直很高,在美国过去30年里,使用避孕药的女性比例在四分之一到近三分之一之间。在其问世近40年后,避孕药的避孕效果已得到证实,其安全性也已得到改善,关注点已从所谓的健康风险转向已记录且实际存在的健康益处。

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