Kaunitz A M
Department of Obstetrics and Gynecology, University of Florida Health Science Center, Jacksonville 32209, USA.
Contraception. 1999 Jan;59(1 Suppl):29S-33S. doi: 10.1016/s0010-7824(98)00135-8.
Many women remain unaware of classic oral contraceptive (OC) noncontraceptive health benefits even as new health advantages emerge from experience and research. An extensive body of evidence has established that OC protect women against dysmenorrhea and menorrhagia, menstrual cycle irregularities, iron deficiency anemia, ectopic pregnancy, pelvic inflammatory disease, ovarian cysts, benign breast disease, endometrial cancer, and ovarian cancer. In addition, the FDA has stated for the first time that an OC-triphasic norgestimate/35 micrograms ethinyl estradiol--is an effective treatment for moderate acne vulgaris. OC use also appears to prevent osteopenia in hypoestrogenic women. In addition to these noncontraceptive health benefits, OC have proven valuable in the management of a variety of gynecologic disorders, including dysfunctional uterine bleeding, persistent anovulation, premature ovarian failure, functional ovarian cysts, pelvic pain (including secondary dysmenorrhea), mittelschmerz, endometriosis, and the control of bleeding in women with blood dyscrasias. Educating healthcare providers and women about these important noncontraceptive health benefits will result in increased compliance, greater continuation, and fewer unintended pregnancies.
尽管从经验和研究中发现了口服避孕药(OC)新的健康益处,但许多女性仍然不知道其经典的非避孕健康益处。大量证据表明,口服避孕药可保护女性免受痛经、月经过多、月经周期不规律、缺铁性贫血、异位妊娠、盆腔炎、卵巢囊肿、良性乳腺疾病、子宫内膜癌和卵巢癌的侵害。此外,美国食品药品监督管理局(FDA)首次声明,一种三相诺孕酯/35微克炔雌醇的口服避孕药是治疗中度寻常痤疮的有效药物。服用口服避孕药似乎还能预防雌激素水平低的女性出现骨质减少。除了这些非避孕健康益处外,口服避孕药在治疗各种妇科疾病方面也已证明具有重要价值,这些疾病包括功能失调性子宫出血、持续性无排卵、卵巢早衰、功能性卵巢囊肿、盆腔疼痛(包括继发性痛经)、排卵期疼痛、子宫内膜异位症以及控制血液系统疾病女性的出血。让医疗保健人员和女性了解这些重要的非避孕健康益处,将提高服药依从性,增加继续服药率,并减少意外怀孕的发生。