Lawrenson R A, Leydon G M, Williams T J, Newson R B, Feher M D
European Institute of Health and Medical Sciences, Guildford, Surrey, UK.
Diabet Med. 1999 May;16(5):395-9. doi: 10.1046/j.1464-5491.1999.00074.x.
To establish the patterns of contraceptive prescribing for women aged 15-49 with Type 1 diabetes mellitus (DM) and compare them with the patterns in women without diabetes.
This was a cross-sectional study using a UK primary care database.
Nine hundred and thirty-eight women with a diagnosis of Type 1 DM were identified. A comparison group of women aged 15-49 without diabetes (n = 10000) were randomly selected from the database. Twenty-five per cent of the women with diabetes and 32% without diabetes were prescribed a hormonal contraceptive in 1994. Women with Type 1 DM were more likely to be prescribed a combined oral contraceptive than a progestogen only pill (POP) but were 2.12 (95% CI 1.65-2.72) times more likely to be prescribed a POP than women without diabetes and were less likely to be prescribed a combined pill - odds ratio 0.53 (95% CI 0.44-0.64). The pregnancy rate in women with Type 1 DM over the age of 25 years was lower than for women without diabetes. Women under 25 years with Type 1 DM seemed more likely to record a pregnancy.
Differences between women with Type 1 DM and those without diabetes highlight the variation in the way that GPs and patients evaluate the risks and benefits when deciding on contraception.
确定15 - 49岁1型糖尿病(DM)女性的避孕处方模式,并与非糖尿病女性的模式进行比较。
这是一项使用英国初级保健数据库的横断面研究。
共识别出938名诊断为1型糖尿病的女性。从数据库中随机选取15 - 49岁无糖尿病的女性作为对照组(n = 10000)。1994年,25%的糖尿病女性和32%的非糖尿病女性被开具了激素避孕药。1型糖尿病女性比仅使用孕激素避孕药(POP)更有可能被开具复方口服避孕药,但她们被开具POP的可能性是非糖尿病女性的2.12倍(95%置信区间1.65 - 2.72),而被开具复方避孕药的可能性较小——优势比为0.53(95%置信区间0.44 - 0.64)。25岁以上1型糖尿病女性的妊娠率低于非糖尿病女性。25岁以下的1型糖尿病女性似乎更有可能记录到妊娠情况。
1型糖尿病女性与非糖尿病女性之间的差异凸显了全科医生和患者在决定避孕时评估风险和益处方式的差异。