Alzieu J P, Mage C, Maes L, de Mûelenaere C
Veterinary Clinic Les Althéas Pamiers, France.
Vet Rec. 1999 Apr 17;144(16):442-4. doi: 10.1136/vr.144.16.442.
One hundred and twenty weaned male lambs, naturally infected with Eimeria species, were used to assess the economic benefits of the prophylactic administration of diclazuril. They were randomly divided into four groups of 30 lambs on the basis of their bodyweight and output of oocysts. The groups were either left untreated (group 1), treated orally with a simple dose of diclazuril at 1 mg/kg (group 2), with two doses two weeks apart (group 3), or with sulphadimethoxine at 50 mg/kg for five consecutive days (group 4). No clinical signs of coccidiosis were observed in any of the groups. The output of oocysts was significantly reduced on day 7 after treatment in group 2, on days 7, 14 and 28 in group 3 and on days 7 and 14 in group 4. No significant differences were found between the treated and untreated groups for bodyweight, carcase weight and carcase classification. The mean fattening period was shorter for the treated lambs (52 and 55 days) than for the untreated controls (60 days). The average growth rate of the lambs treated twice with diclazuril and with sulphadimethoxine was improved and the feed conversion rates of the lambs treated once or twice with diclazuril were 7 per cent and 16 per cent better than that of the untreated lambs.
120只自然感染艾美耳球虫的断奶雄性羔羊用于评估地克珠利预防性给药的经济效益。根据体重和卵囊产量将它们随机分为4组,每组30只羔羊。这些组要么不进行处理(第1组),要么口服1 mg/kg的单剂量地克珠利进行处理(第2组),要么间隔两周分两次给药(第3组),要么连续5天口服50 mg/kg的磺胺二甲氧嘧啶进行处理(第4组)。所有组均未观察到球虫病的临床症状。第2组在处理后第7天、第3组在处理后第7、14和28天以及第4组在处理后第7和14天,卵囊产量显著降低。处理组和未处理组在体重、胴体重和胴体分级方面未发现显著差异。处理过的羔羊的平均育肥期(52天和55天)比未处理的对照组(60天)短。用磺胺二甲氧嘧啶和两次用地克珠利处理的羔羊的平均生长速度提高,一次或两次用地克珠利处理的羔羊的饲料转化率比未处理的羔羊分别高7%和16%。