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Biological effects of an unsaturated trihydroxy acid (PGF2alfa) from normal swine lung.来自正常猪肺的一种不饱和三羟基酸(前列腺素F2α)的生物学效应。
Acta Physiol Scand. 1963 May;58:1-12. doi: 10.1111/j.1748-1716.1963.tb02622.x.
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Quadriceps weakness in knee osteoarthritis: the effect on pain and disability.膝骨关节炎中的股四头肌无力:对疼痛和残疾的影响。
Ann Rheum Dis. 1998 Oct;57(10):588-94. doi: 10.1136/ard.57.10.588.
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Screening for pain in knee osteoarthritis: which question?膝关节骨关节炎疼痛的筛查:该问哪个问题?
Ann Rheum Dis. 1996 Dec;55(12):931-3. doi: 10.1136/ard.55.12.931.
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A randomized trial comparing aerobic exercise and resistance exercise with a health education program in older adults with knee osteoarthritis. The Fitness Arthritis and Seniors Trial (FAST).一项针对老年膝骨关节炎患者,比较有氧运动、抗阻运动与健康教育项目效果的随机试验。健身、关节炎与老年人试验(FAST)。
JAMA. 1997 Jan 1;277(1):25-31.
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Arthritis and exercise: the times they are a-changin'.关节炎与运动:时代正在改变。
Arthritis Care Res. 1996 Apr;9(2):79-81. doi: 10.1002/art.1790090202.
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The effect of isometric quadriceps strength training in mid-range for osteoarthritis of the knee.膝关节骨关节炎中等范围等长股四头肌力量训练的效果
Arthritis Care Res. 1993 Mar;6(1):52-6. doi: 10.1002/art.1790060110.
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The influence of arthrogenous muscle inhibition on quadriceps rehabilitation of patients with early, unilateral osteoarthritic knees.关节源性肌肉抑制对早期单侧膝骨关节炎患者股四头肌康复的影响。
Br J Rheumatol. 1993 Feb;32(2):127-31. doi: 10.1093/rheumatology/32.2.127.
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Home exercises are as effective as outpatient hydrotherapy for osteoarthritis of the hip.
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Disablement associated with rheumatic disorders in a British population: problems with activities of daily living and level of support.英国人群中与风湿性疾病相关的残疾:日常生活活动问题及支持水平
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Effects of a quantitative progressive rehabilitation program applied unilaterally to the osteoarthritic knee.
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家庭锻炼对膝关节骨关节炎疼痛和功能障碍的有效性:一项随机对照试验。

Effectiveness of home exercise on pain and disability from osteoarthritis of the knee: a randomised controlled trial.

作者信息

O'Reilly S C, Muir K R, Doherty M

机构信息

Rheumatology Unit, City Hospital, Nottingham.

出版信息

Ann Rheum Dis. 1999 Jan;58(1):15-9. doi: 10.1136/ard.58.1.15.

DOI:10.1136/ard.58.1.15
PMID:10343535
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1752761/
Abstract

OBJECTIVE

To assess the effect of a home based exercise programme, designed to improve quadriceps strength, on knee pain and disability.

METHODS

191 men and women with knee pain aged 40-80 were recruited from the community and randomised to exercise (n = 113) or no intervention (n = 78). The exercise group performed strengthening exercises daily for six months. The primary outcome measure was change in knee pain (Western Ontario McMaster Osteoarthritis index (WOMAC)). Secondary measures included visual analogue scales (VAS) for pain on stairs and walking and WOMAC physical function scores.

RESULTS

WOMAC pain score reduced by 22.5% in the exercise group and by 6.2% in the control group (between group difference p < 0.05, unpaired t test). VAS scores for pain also reduced in the exercise group compared with the control group (p < 0.05). Physical function scores reduced by 17.4% in the exercise group and were unchanged in controls (p < 0.05).

CONCLUSION

A simple programme of home quadriceps exercises can significantly improve self reported knee pain and function.

摘要

目的

评估一项旨在增强股四头肌力量的家庭锻炼计划对膝关节疼痛及功能障碍的影响。

方法

从社区招募了191名年龄在40至80岁之间的膝关节疼痛患者,随机分为锻炼组(n = 113)和无干预组(n = 78)。锻炼组每天进行强化锻炼,为期六个月。主要结局指标为膝关节疼痛的变化(西安大略和麦克马斯特大学骨关节炎指数(WOMAC))。次要指标包括上下楼梯及行走时疼痛的视觉模拟量表(VAS)评分以及WOMAC身体功能评分。

结果

锻炼组的WOMAC疼痛评分降低了22.5%,对照组降低了6.2%(组间差异p < 0.05,独立样本t检验)。与对照组相比,锻炼组的疼痛VAS评分也有所降低(p < 0.05)。锻炼组的身体功能评分降低了17.4%,而对照组无变化(p < 0.05)。

结论

一项简单的家庭股四头肌锻炼计划可显著改善自我报告的膝关节疼痛及功能。