Stimulation of hamster and human lymphocyte cultures by soluble egg antigens (SEA) of Schistosoma haematobium and S. mansoni.

Soluble egg and adult worm antigen preparations of Schistosoma haematobium and S. mansoni were tested in hamster and human lymphocyte cultures. Primed lymphocytes from infected donors showed a marked blastogenic response to the homologous antigens. A cross-reactivity to the heterologous antigens was seen especially in S. mansoni infected hamsters.