Wright E P, Guthrie C D, Salim D, Hilditch T J, Das P K
Infect Immun. 1982 Apr;36(1):419-22. doi: 10.1128/iai.36.1.419-422.1982.
A preparation of the fluid released upon hatching of the miracidia from Schistosoma mansoni eggs was found to have a potent inhibitory effect on the in vitro activation of hamster lymphocytes by mitogens. The effect was concentration dependent, not cytotoxic, and was the same on cells from healthy and schistosome-infected animals.
研究发现,曼氏血吸虫虫卵孵化时释放的液体提取物对丝裂原体外激活仓鼠淋巴细胞具有显著的抑制作用。该作用呈浓度依赖性,无细胞毒性,且对健康动物和感染血吸虫动物的细胞作用相同。