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简短报告:通过定量血沉棕黄层荧光法诊断蜱传回归热

Short report: Diagnosis of tick-borne relapsing fever by the quantitative buffy coat fluorescence method.

作者信息

Chatel G, Gulletta M, Matteelli A, Marangoni A, Signorini L, Oladeji O, Caligaris S

机构信息

Clinic of Infectious and Tropical Diseases, University of Brescia, Italy.

出版信息

Am J Trop Med Hyg. 1999 May;60(5):738-9. doi: 10.4269/ajtmh.1999.60.738.

DOI:10.4269/ajtmh.1999.60.738
PMID:10344644
Abstract

The quantitative buffy coat (QBC) parasite detection method is a sensitive and specific tool for the diagnosis of malaria parasites. It is also useful for the diagnoses of other hemoparasites, including Trypanosoma, Babesia, and Leptospira. We report a case of relapsing fever diagnosed by this technique in a short-term traveler from Senegal. The diagnosis was confirmed by the standard Giemsa hemoscopy and by the identification of significant titers of antibodies to Borrelia spp. of tick-borne relapsing fevers by specific immunofluorescence and Western blot tests. The QBC technique seems to be useful in the diagnosis of tick-borne relapsing fever in blood samples and should be included in the management of fever in the traveler returning from tropical regions.

摘要

定量血沉棕黄层(QBC)寄生虫检测方法是诊断疟原虫的一种灵敏且特异的工具。它对其他血液寄生虫的诊断也很有用,包括锥虫、巴贝斯虫和钩端螺旋体。我们报告了一例通过该技术诊断出复发性发热的病例,患者是一名来自塞内加尔的短期旅行者。通过标准吉姆萨血涂片检查以及通过特异性免疫荧光和蛋白质印迹试验鉴定出针对蜱传回归热疏螺旋体属的高滴度抗体,确诊了该病例。QBC技术似乎对血液样本中蜱传回归热的诊断有用,应纳入对从热带地区返回的旅行者发热的管理中。

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