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药品参考价格。它们在实际中是如何运作的?

Pharmaceutical reference prices. How do they work in practice?

作者信息

Dickson M, Redwood H

机构信息

Pharmacy Practice Department, College of Pharmacy, University of South Carolina, Columbia, USA.

出版信息

Pharmacoeconomics. 1998 Nov;14(5):471-9. doi: 10.2165/00019053-199814050-00002.

DOI:10.2165/00019053-199814050-00002
PMID:10344913
Abstract

Reference pricing systems are reimbursement ceilings set by payers in an effort to constrain pharmaceutical expenditure for a private or public drug benefit. In recent years, many governments have adopted reference pricing either as a replacement or in addition to product specific price controls. Programme administrators should consider whether these policies are providing the intended benefits or whether there may be a more effective method. This article provides a review of reference pricing in Europe, North America and other countries. There are many similarities in the reference price policies but the markets to which they apply are more likely to be different. The European experience gives a 'once-for-all' lowering effect on pharmaceutical expenditure, often at the expense of compromises on prescribing. In Germany and The Netherlands, reference pricing has been relatively ineffective in lowering expenditure which has led to a succession of other interventions to achieve expenditure control goals. The US also has reference pricing, but it occurs in a very competitive market which may be responsible (at least in part) for the relatively modest growth in expenditure compared with European countries. The review of countries with reference pricing policies suggests that such policies are less effective than competitive markets in moderating pharmaceutical expenditure. Nonetheless, governments continue to pursue reference pricing strategies.

摘要

参考定价系统是支付方设定的报销上限,旨在控制私人或公共药品福利的药品支出。近年来,许多政府已采用参考定价作为产品特定价格管制的替代方案或补充方案。项目管理人员应考虑这些政策是否正在提供预期的效益,或者是否可能存在更有效的方法。本文对欧洲、北美和其他国家的参考定价进行了综述。参考价格政策有许多相似之处,但它们所适用的市场可能更不相同。欧洲的经验对药品支出产生了“一劳永逸”的降低效果,这通常是以牺牲处方妥协为代价的。在德国和荷兰,参考定价在降低支出方面相对无效,这导致了一系列其他干预措施以实现支出控制目标。美国也有参考定价,但它出现在一个竞争非常激烈的市场中,这可能(至少部分)是与欧洲国家相比支出增长相对适度的原因。对实施参考定价政策的国家的综述表明,此类政策在控制药品支出方面不如竞争市场有效。尽管如此,各国政府仍继续推行参考定价策略。

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本文引用的文献

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Approval of new drugs in the United States. Comparison with the United Kingdom, Germany, and Japan.美国新药审批情况。与英国、德国和日本的比较。
JAMA. 1996 Dec 11;276(22):1826-31.
参考定价制度下患者社会经济决定因素对选择仿制药与品牌药的影响:来自比利时处方数据的证据。
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European healthcare policies for controlling drug expenditure.欧洲控制药品支出的医疗政策。
Pharmacoeconomics. 2003;21(2):89-103. doi: 10.2165/00019053-200321020-00002.
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Pharmacoeconomics. 2002;20(9):577-91. doi: 10.2165/00019053-200220090-00002.
8
Impact of reference-based pricing for histamine-2 receptor antagonists and restricted access for proton pump inhibitors in British Columbia.基于参考定价对组胺-2受体拮抗剂的影响以及不列颠哥伦比亚省质子泵抑制剂的受限获取情况。
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CMAJ. 2001 Oct 16;165(8):1011-9.
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Aten Primaria. 2001 Sep 30;28(5):340-8. doi: 10.1016/s0212-6567(01)70386-1.