来自木槿根皮的两种具有生物活性的五环三萜酯。
Two bioactive pentacyclic triterpene esters from the root bark of Hibiscus syriacus.
作者信息
Yun B S, Ryoo I J, Lee I K, Park K H, Choung D H, Han K H, Yoo I D
机构信息
Korea Research Institute of Bioscience and Biotechnology, P.O. Box 115, Yusong, Taejon 305-600, Korea.
出版信息
J Nat Prod. 1999 May;62(5):764-6. doi: 10.1021/np9804637.
Two new triterpene caffeates have been isolated from the root bark of Hibiscus syriacus. Their structures were established through various spectral studies as 3beta,23,28-trihydroxy-12-oleanene 23-caffeate (1) and 3beta,23,28-trihydroxy-12-oleanene 3beta-caffeate (2). Compounds 1 and 2 showed lipid peroxidation inhibitory activity and significant cytotoxicity against a panel of human cancer cell lines.
从木槿的根皮中分离出两种新的三萜咖啡酸酯。通过各种光谱研究确定它们的结构分别为3β,23,28-三羟基-12-齐墩果烯-23-咖啡酸酯（1）和3β,23,28-三羟基-12-齐墩果烯-3β-咖啡酸酯（2）。化合物1和2表现出脂质过氧化抑制活性以及对一组人类癌细胞系的显著细胞毒性。
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